Before taking spironolactone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
You should use spironolactone with caution if you have kidney problems, high levels of potassium in your blood, Addison's disease, if you are unable to urinate, or if you are also taking eplerenone.
This drug can cause hyperkalemia (high potassium levels). While taking this drug, you should watch your potassium intake. You shouldn’t take potassium supplements, eat a diet rich in potassium, or consume salt substitutes containing potassium. Having too much potassium in your body can lead to severe problems. This can even be fatal. Talk to your doctor or a nutritionist if you’re concerned about your potassium intake.
You should not use spironolactone if you are allergic to it, or if you have:
To make sure spironolactone is safe for you, tell your doctor if you have:
Tell your doctor if you are pregnant or plan to become pregnant. Having congestive heart failure, cirrhosis, or uncontrolled high blood pressure during pregnancy may lead to medical problems in the mother or the baby. Your doctor should decide whether you take spironolactone if you are pregnant.
It may not be safe to breastfeed while using spironolactone. Ask your doctor about any risk.
Usual Adult Dose for Edema:
A second diuretic that acts more proximally at the renal tubule may be added if adequate diuresis has not been achieved after 5 days. The dose of this drug should remain unchanged if a second diuretic is added.
Usual Adult Dose for Hypertension:
Usual Adult Dose for Congestive Heart Failure:
Usual Adult Dose for Primary Hyperaldosteronism:
This serves an initial diagnostic measure to provide presumptive evidence of primary hyperaldosteronism while patients are on normal diets and for:
Long test: 400 mg orally per day for 3 to 4 weeks-Short test: 400 mg orally per day for 4 days
Maintenance dose: 100 to 400 mg orally per day until surgery
May be used long-term at the lowest effective dose in patients deemed unsuitable for surgery.
For the long test, correction of hypokalemia and hypertension provides presumptive evidence of primary hyperaldosteronism.-For the short test, increased serum potassium with this drug and a decrease upon discontinuation provide presumptive evidence of primary hyperaldosteronism.
Short-term preoperative treatment of patients with primary hyperaldosteronism.
Spironolactone oral tablet may cause drowsiness. You shouldn’t drive, use machinery, or do similar tasks that require alertness until you know how this drug affects you.
Common side effects that can occur with spironolactone include:
If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist.
Serious side effects
Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following: